TNF alpha (TNF) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, FN, IHC, WB
Recommend Dilution	Immunohistochemsitry on Frozen Sections: The typical starting working dilution is 1/10. Immunohistochemistry on Paraffin Sections: The typical starting working dilution is 1/10. Flow Cytometry: The typical starting working dilution is 1/10. Functional Assays (inhibition of biological activity). Immunoassays. Western blot: The typical starting working dilution is 1/10.
Reactivity	Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Specificity	The antibody reacts with natural and recombinant TNF-alpha and recognizes membrane and receptor bound TNF-alpha. The antibody shows Neutralizing activity.
Formulation	PBS State: Purified State: Liquid 0.2 µm filtered Ig fraction Stabilizer: 0.1% BSA
Concentration	lot specific
Purification	Protein A Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C.
Gene Name	tumor necrosis factor
Database Link	Entrez Gene 21926 Mouse UniProt ID P06804
Background	Tumor Necrosis Factor alpha (TNF-alpha) is a cytokine which has diverse immunomodulatory, anti-tumor and toxic effects. TNF-alpha has been detected in diverse inflammatory status and appears to be a critical mediator in the lethality of septic shock. Furthermore, TNF-alpha has also been found in inflammatory foci such as synovial effusions in rheumatoid arthritis, systemic circulation in septic shock, parasitemia and rejection of renal transplants.
Synonyms	TNF, TNF-a, TNFA, TNFSF2, Cachectin
Reference Data

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