TrkB (NTRK2) (703-707) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blot: 1:500 - 1:1000.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Peptide sequence around aa.703~707 derived from TrkB
Specificity	This antibody detects endogenous levels of total TrkB protein.
Formulation	Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Affinity-chromatography using epitope-specific peptide
Conjugation	Unconjugated
Storage Condition	Store (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Gene Name	neurotrophic receptor tyrosine kinase 2
Database Link	Entrez Gene 18212 MouseEntrez Gene 25054 RatEntrez Gene 4915 Human UniProt ID Q16620
Background	Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.
Synonyms	TRKB, NTRK2
Note	Molecular weight: 145 kDa
Reference Data
Protein Families	Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways	MAPK signaling pathway, Neurotrophin signaling pathway

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