CKII alpha (CSNK2A1) pThr360/pSer362 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blot: 1/1000.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Peptide sequence around phosphorylation site of Threonine 360/Serine 362
Specificity	This antibody detects endogenous level of CK2 only when phosphorylated at thronine 360.
Formulation	PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity Chromatography using epitope-specific peptide
Conjugation	Unconjugated
Storage Condition	Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	casein kinase 2 alpha 1
Database Link	Entrez Gene 12995 MouseEntrez Gene 116549 RatEntrez Gene 1457 Human UniProt ID P68400
Background	Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.
Synonyms	CSNK2A1, CK2A1, CK II alpha
Note	Molecular weight: 42 kDa
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase
Protein Pathways	Adherens junction, Tight junction, Wnt signaling pathway

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