GSTM1 (1-159) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Immunohistochemistry on Paraffin Sections: 10 µg/ml. Western Blot: 1/500 - 1/3000.
Reactivity	Bovine, Human, Mouse, Porcine, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein fragment containing a sequence corresponding to a region within amino acids 1 and 159 of Human GSTM1
Specificity	This antibody reacts to Glutathione S-transferase M1 (GSTM1) at aa 1-159.
Formulation	0.1 M Tris-glycine, pH 7.0 containing 20% Glycerol as stabilizer and 0.01% Thimerosal as preservative State: Aff - Purified State: Liquid purfied Ig fraction
Concentration	lot specific
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Gene Name	glutathione S-transferase mu 1
Database Link	Entrez Gene 14862 MouseEntrez Gene 24423 RatEntrez Gene 2944 Human UniProt ID P09488
Background	An enzyme responsible for the metabolism of a broad range of toxic compounds. Mutations are correlated with increased risk of lung cancer after exposure to environmntal tobacco smoke.
Synonyms	Glutathione S-transferase Mu 1, GST class-mu 1, GSTM1-1, GST1, GSTM1a-1a, GSTM1b-1b, GTH4
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Drug metabolism - cytochrome P450, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450

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