TNFAIP3 Goat Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
Reactivity	Human, Monkey, Rabbit
Host	Goat
Clonality	Polyclonal
Immunogen	TNFAIP3 antibody was raised against synthetic peptide from human TNFAIP3 / A20.
Specificity	This antibody reacts to Tumor Necrosis Factor, Alpha-induced Protein 3 (TNFAIP3).
Formulation	Tris saline buffer, pH 7.3 containing 0.5% BSA and 0.02% sodium azide State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	TNF alpha induced protein 3
Database Link	Entrez Gene 7128 Human UniProt ID P21580
Background	Ubiquitin-editing enzyme that contains both ubiquitin ligase and deubiquitinase activities. Involved in immune and inflammatory responses signaled by cytokines, such as TNF-alpha and IL-1 beta, or pathogens via Toll-like receptors (TLRs) through terminating NF-kappa-B activity. Essential component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways.
Synonyms	OTUD7C, Zinc finger protein A20
Reference Data
Protein Families	Druggable Genome
Protein Pathways	NOD-like receptor signaling pathway

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