Glutathione Peroxidase 3 (GPX3) (102-114) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA: 1/1000. Immunohistochemistry on Paraffin Sections: 5 µg/ml. Western Blot: 1 - 3 µg/ml.
Reactivity	Canine, Human, Mouse, Rat, Bovine, Bat, Equine, Monkey, Porcine
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic peptide from internal region of human GPX3
Specificity	This antibody detects Glutathione peroxidase 3 at aa 102-114. It may cross-react with epididymis-specific GPX5 and olfactory epithelium-speciific GPX6.
Formulation	Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide State: Liquid Ig fraction
Concentration	lot specific
Purification	Immunoaffinity chromatography
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	glutathione peroxidase 3
Database Link	Entrez Gene 14778 MouseEntrez Gene 64317 RatEntrez Gene 2878 Human UniProt ID P22352
Background	Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme. GPX3 expression appears to be tissue-specific.
Synonyms	GPX-3, GPXP, GSHPx-3, GPx-3, GSHPx-P, GSHPXP, GPx-P, GPXP
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Arachidonic acid metabolism, Glutathione metabolism

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