Proteasome subunit beta type 4 (PSMB4) (230-239) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	Peptide ELISA: Detection limit: 1/8000. Western blot: 0.1-0.3 µg/ml. Approx 25-26kDa band observed in lysates of cell lines HEK293, HeLa, and K562 and in Mouse and Rat Liver lysates.
Reactivity	Bovine, Canine, Human, Mouse, Rabbit, Rat
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence (230-239) from the internal region of the protein sequence according to NP_002787.2.
Specificity	Recognizes PSMB4 (aa 230-239).
Formulation	Tris saline, pH~7.3 State: Aff - Purified State: Liquid purified IgG fraction Stabilizer: 0.5% BSA Preservative: 0.02% Sodium Azide
Concentration	lot specific
Purification	Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	proteasome subunit beta 4
Database Link	Entrez Gene 5692 Human UniProt ID P28070
Background	The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.
Synonyms	Proteasome subunit beta type-4, Proteasome beta chain, HsBPROS26, PROS-26, Macropain beta chain, Proteasome chain 3, HsN3
Note	Calculated Molecular Weight: 29.1kDa (NP_002787.2).
Reference Data

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