Adrenomedullin (ADM) Rabbit Polyclonal Antibody
CAT#: AP20574PU-N
Adrenomedullin (ADM) rabbit polyclonal antibody, Aff - Purified
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CNY 4,640.00
货期*
2周
规格
Specifications
Product Data | |
Applications | IHC |
Recommend Dilution | Immunohistochemistry on Paraffin Sections: 1/50-1/200. |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide, corresponding to amino acids 70-120 of Human ADM. |
Specificity | This antibody detects endogenous levels of ADM protein. (region surrounding asn100) |
Formulation | PBS, pH~7.2 State: Aff - Purified State: Liquid purified Ig fraction (> 95% by SDS-PAGE) Preservative: 0.05% Sodium Azide |
Concentration | 1.0 mg/ml |
Purification | Affinity Chromatography using epitope-specific immunogen |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | adrenomedullin |
Database Link | |
Background | Adrenomedullin (ADM), a vasodilator produced by most contractile cells, is characterized by persistent hypotensive activity. ADM is involved in the regulation of fluid and electrolyte homeostasis and in the maintenance of cardiovascular functioning. In hypertensive patients, the level of ADM in plasma is upregulated. Natriuresis is a common systemic manifestation of aneurysmal subarachnoid hemorrhage. ADM has strong natriuretic actions. ADM-induced natriuresis is caused by an increase in glomerular filtration rate and a decrease in distal tubular sodium reabsorption. ADM is present both in the periphery and brain, and can exert central effects such as decreasing food ingestion. |
Synonyms | adrenomedullin; AM; preproadrenomedullin |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein |
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