Eph receptor A2 (EPHA2) (+EPHA3/4) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	Western blot: 1/500-1/1000. Immunoflourescence: 1/50-1/200.
Reactivity	Human, Rat
Host	Rabbit
Clonality	Polyclonal
Specificity	This antibody detects endogenous levels of EphA2/3/4 protein.
Formulation	Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2 State: Aff - Purified State: Liquid purified Ig fraction
Concentration	1.0 mg/ml
Purification	Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen, purity is > 95% (by SDS-PAGE)
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	~ 112 kDa
Gene Name	EPH receptor A2
Database Link	Entrez Gene 366492 RatEntrez Gene 1969 Human UniProt ID P29317
Background	EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
Synonyms	Ephrin type-A receptor 2, Epithelial cell kinase, Eph receptor A2
Reference Data
Protein Families	Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways	Axon guidance

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