CD146 (MCAM) Rabbit Polyclonal Antibody

CAT#: AP18112PU-N

CD146 (MCAM) rabbit polyclonal antibody



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CNY 6,160.00


货期*
5周

规格
    • 400 ul

Cited in 2 publications.

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Specifications

Product Data
Applications WB
Recommend Dilution ELISA: 1/1,000.
Western blotting: 1/50 - 1/100.
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide selected from the Center region of human MCAM
Specificity This antibody reacts to CD146.
Formulation PBS with 0.09% (W/V) sodium azide
State: Liquid purified Ig
Concentration lot specific
Purification Saturated Ammonium Sulfate (SAS) precipitation
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name melanoma cell adhesion molecule
Background MCAM plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. It could be an adhesion molecule active in neural crest cells during embryonic development. It acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.
Synonyms MCAM, MUC18, CD146
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (2)

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