ZCH11 (ZCCHC11) (C-term) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC
Recommend Dilution	Peptide ELISA: Limit Dlution: 1/16000. Immunohistochemisry on Paraffin Sections: 2-6 µg/ml. In paraffin embedded Human Lymph Node shows nuclear staining of select lymphocytes and staining of macrophages.
Reactivity	Bovine, Canine, Human, Mouse, Rat
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide from the C Terminus of the protein according to NP_001009881.1, NP_056084.1 and NP_001009882.1.
Specificity	This antibody is expected to recognize all 3 reported isoforms.
Formulation	Tris saline, pH~7.3 with 0.02% Sodium Azide and 0.5% BSA State: Aff - Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	zinc finger CCHC-type containing 11
Database Link	Entrez Gene 23318 Human UniProt ID Q5TAX3
Background	ZCH11 is known to direct cytokine expression by uridylating cytokine-targeting miRNAs. ZCH11 is a ribonucleotidyltransferase with a preference for uridine and is essential for maintaining the poly(A) tail length and stability of transcripts for interleukin-6 (IL-6), plus other specific cytokines.
Synonyms	Terminal uridylyltransferase 4, Kiaa0191, Tut4
Reference Data

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