MET pTyr1349 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Western Blot: 1/1000 Immunohistochemistry: 1/50~1/100.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	This antibody is generated from rabbits immunized with a 4=4 Chain MAPS conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1349 of human MET. Synthetic phosphopeptide was selected from region 1345~1357 of human MET.
Specificity	This antibody detects HGF Receptor (MET) pTyr1349. Predicted to cross react with Mouse and Rabbit (100% Antigen Homology).
Formulation	PBS with 0.09% (W/V) Sodium Azide as preservative. State: Aff - Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	MET proto-oncogene, receptor tyrosine kinase
Database Link	Entrez Gene 4233 Human UniProt ID P08581
Background	The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma.
Synonyms	Hepatocyte growth factor receptor, MET, Scatter factor receptor, HGF/SF receptor, c-Met
Note	Molecular weight: 155527 Da
Reference Data

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