SULT2A1 (C-term) Rabbit Polyclonal Antibody
CAT#: AP12291PU-N
SULT2A1 (C-term) rabbit polyclonal antibody, Purified
Need it in bulk or conjugated?
Get a free quote
CNY 6,160.00
货期*
5周
规格
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | ELISA: 1/1,000. Western Blot: 1/100-1/500. |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human SULT2A. |
Specificity | This antibody detects SULT2A (C-term). |
Formulation | PBS with 0.09% (W/V) Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction. |
Concentration | lot specific |
Purification | Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | sulfotransferase family 2A member 1 |
Database Link | |
Background | One of the major roles of the sulfotransferases (ST) in the metabolism of drugs and endogenous compounds is the conversion of these substances into more hydrophilic water-soluble sulfate conjugates that can be easily excreted. Sulfation may also play a regulatory role for many endogenous compounds, such as steroids and neurotransmitters, by altering the biologic properties of these compounds. Otterness et al. (1992), Kong et al. (1992), and Comer et al. (1993) reported the cloning of cDNAs encoding liver dehydroepiandrosterone (DHEA) sulfotransferase. The predicted protein has 285 amino acids. Although Northern blot analysis of human liver RNA detected transcripts of 3 different sizes, Southern blot analysis of human DNA suggested that only 1 gene is present in the genome. This gene has an important role in the sulfation of both bile acids and steroids in the liver and adrenals. The human adrenal form of this enzyme is physically, immunologically, and kinetically similar, perhaps identical, to the liver form. Dehydroepiandrosterone sulfate is quantitatively one of the major steroids secreted from the adrenal cortex. |
Synonyms | Sulfotransferase 2A1, ST2A1, Bile salt sulfotransferase, Dehydroepiandrosterone sulfotransferase, DHEA-ST, Hydroxysteroid Sulfotransferase |
Note | Molecular weight: 33648 Da |
Reference Data |
Documents
Product Manuals |
FAQs |
SDS |
Resources
抗体相关资料 |
其它SULT2A1产品
Customer
Reviews
Loading...