AGL (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunofluorescence: See: Cheng, Alan, et al. Genes & Dev. 2007 Oct 01;21(19):2399-2409.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 1487~1516 amino acids from the C-terminal region of Human AGL
Specificity	This antibody is specific to AGL/GDE (C-term).
Formulation	PBS with 0.09% (W/V) Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Protein A Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
Database Link	Entrez Gene 178 Human UniProt ID P35573
Background	AGL is a glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in the AGL gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing.
Synonyms	Glycogen debranching enzyme
Note	Predicted Molecular weight: 174764 Da
Reference Data

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