YBX2 (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	ELISA 1:1,000. Immunohistochemistry 1:10 - 1:50.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human YBX2.
Specificity	This antibody detects YBX2 at C-term.
Formulation	PBS with 0.09% (W/V) sodium azide State: Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	Y-box binding protein 2
Database Link	Entrez Gene 51087 Human UniProt ID Q9Y2T7
Background	YBX2 is a major constituent of messenger ribonucleoprotein particles (mRNPs). It is nvolved in the regulation of the stability and/or translation of germ cell mRNAs. It binds to Y-box consensus promoter element and to full length mRNA with high affinity in a sequence-independent manner. It binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. YBX2 may mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay.
Synonyms	Contrin, DBPC, CSDA3, MSY2
Note	Molecular weight: 38518 Da
Reference Data

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