EHMT1/GLP (EHMT1) Rabbit Polyclonal Antibody
CAT#: AP11093PU-N
EHMT1/GLP (EHMT1) rabbit polyclonal antibody, Purified
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CNY 6,160.00
货期*
5周
规格
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | ELISA: 1/1000. Western Blot: 1/100-1/500. |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 956~986 amino acids from the Center region of Human EUHMTASE1 |
Specificity | This antibody is specific to Human EUHMTASE1 (Center). |
Formulation | PBS containing 0.09% (W/V) Sodium Azide as preservative State: Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | euchromatic histone lysine methyltransferase 1 |
Database Link | |
Background | EHMT1, also known as EUHMTASE1, is a histone methyltransferase. This protein methylates 'Lys-9' of histone H3 in vitro. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT1 is Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle. |
Synonyms | EUHMTASE1, GLP, KIAA1876, KMT1D, Eu-HMTase1, G9a-like protein 1, GLP, GLP1, H3-K9-HMTase 5 |
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