Neuropeptide Y (NPY) (68-97) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC
Recommend Dilution	Immunofluorescence: 1/400-1/800 with overnight incubation at 2-8°C. Immunohistochemistry on Frozen Sections. Positive Control: Stefanini-fixed sections of rat small intestine.
Reactivity	Human, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic Prepro-NPY 68-97 (C-PON).
Specificity	Neuropeptide Y is a peptide belonging to the PP-family and occurs in neurons and adrenal medullary cells. Antisera raised against NPY often cross-react with PP and PYY. This antiserum was raised using a synthetic peptide from the prepro-NPY sequence which has no homologies to PP and NPY. Absorption with 10-100 µg immunogen per ml diluted antiserum abolishes the staining.
Formulation	State: Serum State: Lyophilized Undiluted Serum
Reconstitution Method	Dissolve the antiserum in 50-100 µl distilled water, and dilute further in 0.1M PBS with 1% BSA and 0.09% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	neuropeptide Y
Database Link	Entrez Gene 24604 RatEntrez Gene 4852 Human UniProt ID P01303
Background	Neuropeptide Y (NPY) is the most abundant neuropeptide in the brain and is known to function as a potent stimulator of feeding behavior. It is a member of a family of proteins that include pancreatic polypeptide, seminal plasmin and peptide YY. In addition to its function in the control of energy balance, several other physiological roles have been attributed to NPY, including involvement in circadian rhythms, sexual function, anxiety responses and vascular resistance.
Synonyms	Prepro-NPY, C-PON, CPON
Reference Data
Protein Families	Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways	Adipocytokine signaling pathway

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