MARK2 pThr595 Rabbit Polyclonal Antibody

CAT#: AP09297PU-N

MARK2 pThr595 rabbit polyclonal antibody, Aff - Purified



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CNY 8,025.00


货期*
4周

规格
    • 100 ug

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Specifications

Product Data
Applications ELISA, WB
Recommend Dilution ELISA: 1/1,000 - 1/3,000.
Western Blot: 1/250 - 1/1,000.
Reactivity Bovine, Canine, Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to amino acids surrounding T595 of Human MARK2 isoform a. The immunogen peptide was phosphorylated at the residue corresponding to T595
Specificity This antibody is directed against the phosphorylated form of MARK2 at thepT595 residue.
Formulation 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01% (w/v) Sodium Azide
State: Aff - Purified
State: Liquid purified Ig
Concentration lot specific
Purification Affinity chromatography
Conjugation Unconjugated
Storage Condition Store the antibody at -20°C.
Avoid repeated freezing and thawing.
Gene Name microtubule affinity regulating kinase 2
Background This antibody recognizes a regulatory phosphorylation on a kinase that is critical to regulation of microtubules, cell cycle and immune responses. MARK2 refers to MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens]. EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, microtubule stability and cancer. Several cDNA clones have been isolated that encode two isoforms of the human ser/thr protein kinase EMK1 called MARK2. These isoforms were characterized by the presence of a 162-bp alternative exon that gives rise to two forms, one containing the exon and the other one lacking it. Both forms were found to be co-expressed in a number of selected cell lines and tissue samples. Human MARK2 was shown to be encoded by a single mRNA that is ubiquitously expressed. This transcription variant includes the alternative exon in the coding region and therefore codes for a longer protein. Multiple splice variants exist for this protein.
Synonyms Serine/threonine-protein kinase, 2, ELKL motif kinase, EMK1, PAR1 homolog, MARK2, EMK1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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