SNAP25 (193-206) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA: 1/32000. Immunohistochemistry on Paraffin Sections: 2.5 µg/ml. Western Blot: 0.01 - 0.03 µg/ml.
Reactivity	Canine, Human, Mouse, Rat, Bovine, Bat, Chicken, Equine, Hamster, Monkey, Rabbit, Zebrafish
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic peptide from the C-terminus of human SNAP25
Specificity	Recognizes Synaptosomal Associated Protein 25 (SNAP25) at aa 193-206.
Formulation	Tris Saline Buffer, pH 7.3 containing 0.02% Sodium Azide as preservative and 0.5% BSA as stabilizer State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	synaptosome associated protein 25kDa
Database Link	Entrez Gene 6616 Human UniProt ID P60880
Background	SNAP25 (Synaptosome-Associated Protein of 25 kDa) is a membrane bound, pre-synaptic nerve terminal protein that plays an essential role in synaptic vesicle fusion and exocytosis. It is part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. SNAP25 is involved in the molecular regulation of neurotransmitter release. It is thought to play an important role in the synaptic function of specific neuronal systems and it associates with proteins involved in vesicle docking and membrane fusion. SNAP25 exists as two alternatively spliced isoforms, SNAP25A and SNAP25B. These isoforms are differentially expressed in neurons and neuroendocrine cells and they differ by 9 amino acids in the central portion of the protein.
Synonyms	SNAP-25, SUP, SNAP, Super Protein, RIC4, ric-4
Reference Data

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