TACI (TNFRSF13B) (116-132) Rabbit Polyclonal Antibody

CAT#: AP08485PU-N

TACI (TNFRSF13B) (116-132) rabbit polyclonal antibody, Aff - Purified



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CNY 5,511.00


货期*
5周

规格
    • 50 ug

Product images

Specifications

Product Data
Applications FC, IHC, WB
Recommend Dilution Flow Cytometry.
Immunohistochemistry on Paraffin Sections: 5 µg/ml.
Western Blot: 5 µg/ml.
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to amino acids 116-132 of human TACI.
Specificity This antibody recognizes CD267/TACI.
Formulation PBS containing 0.2% Gelatin as stabilizer and 0.05% Sodium Azide as preservative.
State: Aff - Purified
State: Liquid purified Ig fraction.
Concentration lot specific
Purification Protein G Chromatography.
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name tumor necrosis factor receptor superfamily member 13B
Background Simultaneously four different laboratories identified a a new member of the tumor necrosis factor (TNF) family. This has been named as TALL-1, THANK (TNF homologue that activates apoptosis, nuclear factor-kappaB, and c-Jun NH2-terminal kinase, BAFF (for B cell activating factor belonging to the TNF family) and BlyS (B lymphocyte stimulator). Membrane-bound BAFF is processed and secreted through the action of a protease whose specificity matches that of the furin family of proprotein convertases. The receptor for BlyS/BAFF appears to be expressed predominantly on B cells and activated T cells. Recently two orphan receptors TACI and BCMA have been shown to be receptors for BlyS/BAFF. TACI is expressed on B cells and signals through CAML, activating the transcription factors NF-AT, NF-kB, and AP-1. TACI is a type III transmembrane protein, as defined by the lack of a cleaved signal sequence and its N-terminal extracellular exposure. The cDNA codes for 293 amino acids with predicted molecular weight of approximately 32 kDa.
Synonyms TNFRSF13B
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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