Luteinizing Hormone beta (LHB) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC
Recommend Dilution	Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections and cell smears): 1/100-1/500 using streptavidin~biotin system or polymer system. Positive Control: Human anterior pituitary.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	LH beta.
Specificity	This antibody stains both free and intact LH and is useful for the classification of pituitary adenomas and tumors of the pituitary. Cellular Localization: Cytoplasmic.
Formulation	10 mM PO4, 150 mM NaCl, pH 7.4 containing 0.05% Sodium Azide as preservative and 1% BSA as stabilizer. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Protein A Chromatography.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	luteinizing hormone beta polypeptide
Database Link	Entrez Gene 3972 Human UniProt ID P01229
Background	Luteinizing Hormone (LH) is a tropic hormone which modulates the secretory activity of other endocrine glands. This glycoprotein hormone is produced in the anterior hypophysis of the pituitary gland. In the female an acute rise of LH the LH surge – triggers ovulation. In the male, where LH had also been called Interstitial Cell Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. The alpha subunits of LH, FSH, TSH, and hCG are identical, and contain 92 amino acids, the beta subunit vary. LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action. and is responsible for interaction with the LH receptor.
Synonyms	LHB, LH-B, LSH-beta, Luteinizing hormone subunit beta, Lutropin beta chain, Lutropin subunit beta
Reference Data

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