Calcitonin (CALCA) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	Immunohistochemistry: 1/50-1/200 using polymer or streptavidin biotin system for 30 minutes at room temperature. Positive control: Human thyroid or medulary carcinoma.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide from human Calcitonin conjugated to carrier protein.
Specificity	This antibody is specific for Calcitonin. Cellular localization: Cytoplasmic.
Formulation	10 mM PO4, 150 mM NaCl, pH 7.4 containing 0.05% Sodium Azide as preservative. State: Ig Fraction State: Total Ig fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	calcitonin related polypeptide alpha
Database Link	Entrez Gene 796 Human UniProt ID P06881
Background	Calcitonin is a 32-amino acid polypeptide hormone that is produced in human primarily by the parafollicular (also known as C-cells) of the thyroid, and in many other animals in the ultimobranchial body It acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH) Calcitonin staining can detect C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors.
Synonyms	CALCA, CALC1
Reference Data

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