ERG (C-term) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC
Recommend Dilution	ELISA: 1/16000. Immunohistochemistry on Paraffin Sections: 10 µg/ml.
Reactivity	Human, Monkey
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic peptide from the C-terminus of human ERG (NP_891548.1; NP_004440.1; NP_001129626.1; NP_001129627.1)
Specificity	This antibody is expected to recognise both reported isoforms (NP_891548.1; NP_004440.1).
Formulation	Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	ERG, ETS transcription factor
Database Link	Entrez Gene 2078 Human UniProt ID P11308
Background	ERG is a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins.
Synonyms	Transcriptional regulator ERG, Transforming protein ERG
Reference Data

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