IL24 (100-150) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IHC, WB
Recommend Dilution	Flow Cytometry. Immunohistochemistry on Paraffin Sections: 10 µg/ml. Western Blot: 0.5 - 3 µg/ml.
Reactivity	Human, Monkey
Host	Rabbit
Clonality	Polyclonal
Immunogen	Amino acids 123-136 of human IL-24
Specificity	This antibody recognizes Interleukin 24 (IL24/Mda-7) at amino acids 100-150.
Formulation	PBS State: Purified State: Liquid purified IgG fraction Stabilizer: 0.2% Gelatin Preservative: 0.05% Sodium Azide
Concentration	lot specific
Purification	Protein G Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C to -70°C for longer. Avoid repeated freezing and thawing.
Gene Name	interleukin 24
Database Link	Entrez Gene 11009 Human UniProt ID Q13007
Background	Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.
Synonyms	IL-24, MDA7, ST16
Reference Data

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