SLPI Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Western Blot: 1.0 - 2.0 µg/ml; detects a band of approximately 14kDa in Daudi cell lysates. Immunohistochemistry on paraffin sections (requires antigen retrieval using heat treatment prior to staining).
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	A 17 amino acid peptide located near the centre of human SLPI.
Specificity	This antibody recognises secretory leukocyte protease inhibitor (SLPI).
Formulation	Phosphate buffered saline containing 0.02% Sodium Azide State: Purified State: Liquid purified IgG
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	secretory leukocyte peptidase inhibitor
Database Link	Entrez Gene 6590 Human UniProt ID P03973
Background	SLPI is a 14kD non-glycosylated protein produced by secretory cells in the respiratory, genital and lacrimal glands, and by macrophages, B-cells and neutrophils. The functions of SLPI are diverse. The SLPI protein inhibits protease activity at sites of inflammation, protecting tissues against protease mediated damage and it possesses anti-microbial/anti-viral activity. In addition, SLPI has been reported to exhibit anti-inflammatory properties, regulating lipopolysaccharide induced activation of NF-kappa beta in peripheral blood monocytes.
Synonyms	SLPI, WAP4, WFDC4
Reference Data

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