GSK3 beta (GSK3B) pSer9 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western Blot: 1:1000; detects a band of approximately 46kDa in rat cortex cell lysates.
Reactivity	Bovine, Canine, Chicken, Human, Monkey, Mouse, Rat, Xenopus, Zebrafish
Host	Rabbit
Clonality	Polyclonal
Immunogen	Phosphopeptide corresponding to amino acid sequence surrounding phoshorylated seine 9 of rat GSK3 beta.
Specificity	This antibody recognises glycogen synthase 3 (GSK3) beta phosphorylated at serine 9.
Formulation	10mM Hepes pH7.5 containing 0.09% Sodium Azide (NaN3), 50% Glycerol and 0.01% Bovine Serum Albumin State: Purified State: Liquid purified IgG
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	glycogen synthase kinase 3 beta
Database Link	Entrez Gene 2932 Human UniProt ID P49841
Background	GSK3 is a 46 kDa member of the serine/threonine protein kinase family. Two isforms of GSK3 exist, alpha and beta. GSK3 beta is expressed in the testis, thymus, prostate, and ovary as well as being expressed at low levels in lung, brain and kidney tissue. GSK3 beta is involved in many signalling pathways including energy metabolism, body pattern formation and microtubule growth and stability (which aids axon growth). GSK3 beta is also thought to be involved in oncogenesis and the hormonal control of several regulatory proteins including glycogen synthase. Phosphorylation of serine-9 inhibits GSK3 beta function.
Synonyms	GSK-3 beta, Glycogen synthase kinase-3 beta, GSK3B
Reference Data

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