TIM 1 (HAVCR1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blot: 1.0 - 2.0 µg/ml; detects a band of approximately 49kDa in human uterus tissue lysate.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	16 amino acid peptide sequence near the centre of human TIM-1.
Specificity	This antibody detects T cell immunoglobulin mucin-1 (TIM-1), which was first identified as the receptor used by hepatitis A for viral entry (it is also known as the hepatitis A virus cellular receptor- HAVCR).
Formulation	Phosphate buffered saline containing 0.02% Sodium Azide State: Purified State: Liquid purified IgG
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for up to one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	hepatitis A virus cellular receptor 1
Database Link	Entrez Gene 26762 Human UniProt ID Q96D42
Background	TIM-1 is a key cell surface protein that binds TIM-4, leading to T cell proliferation and T helper type 2 (Th2) cytokine production. TIM-1 has also been shown to bind and activate macrophages. Two splice variants for human TIM-1 exist; TIM-1a is predominantly expressed in the liver, whilst TIM-1b is expressed in the kidney. Expression of TIM-1 in the kidney is thought to be upregulated in damaged tissue, and is thought to assist healing. TIM-1 polymorphisms are associated with asthma.
Synonyms	TIMD-1, TIM1, TIM-1, T cell membrane protein 1, HAVCR-1
Reference Data

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