Sumo 1 (SUMO1) (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	Western blot: 0.5 - 1.0 µg/ml; detects a band of approximately 15kDa in HL60 cell lysates. Immunocytochemistry.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	14 amino acid peptide sequence near the amino terminus of human SUMO-1
Specificity	This antibody detects an epitope within the N-terminal (NT) region of small ubiquitin-related modifier-1 (SUMO-1).
Formulation	Phosphate buffered saline containing 0.02% Sodium Azide State: Purified State: Liquid purified IgG
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	small ubiquitin-like modifier 1
Database Link	Entrez Gene 7341 Human UniProt ID P63165
Background	SUMO-1 is an 11kD protein which structurally related to ubiquitin, and is added to proteins as a form of post-translational modification known as sumoylation. Sumoylation can be cell cycle regulated, stimulated upon stress or induced by DNA damage, and binding elicits individual effects for each protein. Effects include changes to protein stability, nuclear-cytosolic transport, and transcriptional regulation (mostly transcriptional repression). Alternate transcriptional splice variants encoding different isoforms have been characterized.
Synonyms	SMT3C, SMT3H3, UBL1, GMP1, SMT3 homolog 3, Sentrin
Reference Data

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