EDA2R Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Western blot: 0.5 - 2.0 µg/ml; detects a band of approximately 33kDa in 293 cell lysates.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant human XEDAR.
Specificity	This antibody detects human X-linked ectodermal dysplasia receptor (XEDAR).
Formulation	Phosphate buffered saline containing 0.02% Sodium Azide State: Purified State: Liquid purified IgG
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for up to one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	ectodysplasin A2 receptor
Database Link	Entrez Gene 60401 Human UniProt ID Q9HAV5
Background	XEDAR is a 33kD type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily. XEDAR is a homologue of the ectodermal dysplasia receptor (EDAR), and binds to an isoform of ectodysplasin termed EDA-A2. Binding of ectodysplasin to XEDAR results in the induction of apoptosis, and is thought to be involved ectodermal organ development. New evidence suggests XEDAR may also be involved in skeletal muscle development. Two predominant isoforms of XEDAR exist; XEDAR-s and XEDAR-L, produced by alternative splicing.
Synonyms	XEDAR, EDA-A2 receptor, UNQ2448/PRO5727/PRO34080
Reference Data

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