MARK3 Sheep Polyclonal Antibody

Specifications

Product Data
Applications	IP, WB
Recommend Dilution	Western Blot: 1 to 5 µg/ml. Detects c-tak1 in RKO and HCT116 cell lysates POSITIVE CONTROL: Recombinant His-tagged C-TAK1 protein.
Reactivity	Human
Host	Sheep
Clonality	Polyclonal
Immunogen	Recombinant, full-length His-tagged human C-TAK1 produced in E. Coli.
Specificity	This antibody reacts to C-TAK1.
Formulation	Phosphate buffered saline with 0.08% sodium azide State: Purified State: Liquid purified Ig (0.2 µm sterile filtered)
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	The antibody can be shipped at ambient temperature. Store (in aliquots) at -20°C only. Avoid repeated freezing and thawing.
Gene Name	microtubule affinity regulating kinase 3
Database Link	Entrez Gene 4140 Human UniProt ID P27448
Background	C-TAK1 (Cdc25C associated protein kinase) is a ubiquitously expressed protein kinase found in human tissues and cell lines and can phosphorylate Cdc25C on serine 216 in vitro. C-TAK1 is distinct from the DNA damage checkpoint kinase Chk1 and may regulate interactions between Cdc25C and 14-3-3 in vivo by phosphorylating Cdc25C at serine 216.
Synonyms	CTAK1, C-TAK1, MAP/microtubule affinity-regulating kinase 3, Serine/threonine-protein kinase p78, PAR-1, STK10
Reference Data

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