Eph receptor B1 (EPHB1) (EXT Region) Sheep Polyclonal Antibody

CAT#: AP05060PU-N

Eph receptor B1 (EPHB1) (EXT Region) sheep polyclonal antibody, Purified



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CNY 5,937.00


货期*
4周

规格
    • 250 ug

Product images

Specifications

Product Data
Applications IP, WB
Recommend Dilution Western Blot: 1 - 10 µg/ml.
Immunoprecipitation: 10 - 20 µg/ml.
Reactivity Human
Host Sheep
Clonality Polyclonal
Immunogen A GST fusion protein ephB1 (Elk receptor) corresponding to amino acid
Specificity This antibody reacts to ephB1 (Elk receptor) - EXT.
Formulation Phosphate buffered saline with 0.08% sodium azide
State: Purified
State: Liquid purified Ig (0.2µm sterile filtered)
Concentration lot specific
Conjugation Unconjugated
Storage Condition Store the antibody at -20°C.
Avoid repeated freezing and thawing.
Gene Name EPH receptor B1
Background The immunogen used for the anti-human ephB1 (Elk receptor) -EXT region was a GST fusion protein ephB1 (Elk receptor) -EXT corresponding to amino acid sequence 16-351 of the N terminus region and having a molecular weight of 116 kD. ephB1, previously known as Elk(eph-like kinase), is a receptor tyrosine kinase of the highly tissue restricted family of eph proteins. EphB1 and other ephB family members are type 1 membrane spanning proteins, comprised of immunoglobulin, fibronectin type III, and cysteine rich subdomains in the ecto domain, and the single uninterrupted cytoplasmic tyrosine kinase domain upstream of a carboxyterminal sterile alpha motif (SAM) domain. ephB family proteins bind ephrins of the B class, ligands that are also transmembrane spanning proteins capable of transmitting signals. ephB1 is expressed predominantly in developing neural structures in embryos, and in vascular epithelium of kidney, and other tissues. Upon binding to alternatively oligomerized ephrin B1, ephB1 signals regulation of cell attachment and cellcell assembly. Members of this protein family are implicated in neuronal and vascular cell targeting.
Synonyms EPHT2, NET, HEK6, ELK, EPH2, Ephrin type-B receptor 1
Reference Data
Protein Families Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways Axon guidance
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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