PPP2R5D Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western Blotting. Immunofluorescence.
Reactivity	Bovine, Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide conjugated to KLH derived from the N-terminus of PP2A/B delta
Specificity	This antibody reacts to PP 2A/B delta.
Formulation	Phosphate buffered saline with 0.08% sodium azide State: Purified State: Liquid purified Ig (0.2 µm sterile filtered)
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	The antibody can be shipped at ambient temperature. Store (in aliquots) at -20°C only. Avoid repeated freezing and thawing.
Gene Name	protein phosphatase 2 regulatory subunit B'delta
Database Link	Entrez Gene 21770 MouseEntrez Gene 363193 RatEntrez Gene 5528 Human UniProt ID Q14738
Background	PP2A is a heterotrimeric phosphatase, ccomposed of A, B and C subunits. The structural A and catalytic C subunits form the constitutive core of the enzyme, which associates with one of a large number of regulatory B subunits. Three families of B subunits have been identified thus far. The prototypical B (or PR55) family of subunits is encoded by three genes, Ba, Bb and Bg . The B' (or B56) family consists of at least seven splice variants derived from five genes. RNA's for the two members of the B family, PR72 and PR130, arise by alternative splicing or use of alternate transcription start sites from the same gene. Primary structures as well as functions of B and B' subunits are conserved from yeast to mammals. Bd is a novel isoform of the B class of PP2A regulatory subunits. It is widely expressed in rat tissues and appears to be involved in targeting PP2A to the cytosolic compartment.
Synonyms	Protein phosphatase 2A, PP2A B subunit B'delta isoform, PP2A B subunit B56 delta isoform, PP2A B subunit PR61 delta isoform, PP2A B subunit R5 delta isoform
Reference Data
Protein Families	Phosphatase
Protein Pathways	Oocyte meiosis, Wnt signaling pathway

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