Her2 (ERBB2) Sheep Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blot: 5 - 10 µg/ml. Positive Control: Breast carcinomas.
Reactivity	Human
Host	Sheep
Clonality	Polyclonal
Immunogen	Full-length recombinant c-erbB-2/HER2/neu protein.
Specificity	This antibody reacts to c-erbB-2/HER2/neu.
Formulation	Phosphate buffered saline with 0.08% sodium azide State: Purified State: Liquid purified Ig
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	The antibody can be shipped at ambient temperature. Store (in aliquots) at -20°C only. Avoid repeated freezing and thawing.
Gene Name	erb-b2 receptor tyrosine kinase 2
Database Link	Entrez Gene 2064 Human UniProt ID P04626
Background	c-erbB-2 is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein.
Synonyms	HER-2, NEU, p185erbB2, NGL, c-erbB-2, MNL19
Reference Data

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