TGFBR2 (77-148) Sheep Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	Western Blot: 1:100. Immunohistology.
Reactivity	Chicken
Host	Sheep
Clonality	Polyclonal
Specificity	This antibody reacts to TGF Type II Receptor a.a. 77 - 148.
Formulation	Phosphate buffered saline with 0.08% sodium azide State: Purified State: Liquid purified Ig (0.2µm sterile filtered)
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Gene Name	transforming growth factor, beta receptor II (70/80kDa)
Database Link	Entrez Gene 396399 Chicken UniProt ID Q90999
Background	The immunogen used was a GST fusion protein containing chick transforming growth factor b type II receptor a.a.77-148. Epithelial-mesenchymal transformation is a critical event in the development of many organ systems including heart. Transforming Growth Factor b (TGFb) is one of a number of factors that mediates this transformation. Antibodies directed against TGFb Type II recepttor block both the endicardial cell activation and subsequent migration that constitute transformation in the chick atrioventricular (AV) cushion.
Synonyms	TGF-beta receptor type-2, TGF-beta receptor type II, TGF-beta type II receptor, TbetaR-II, TGFR-2
Reference Data

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