FOXO1 (254-258) Rabbit Polyclonal Antibody

CAT#: AP02666PU-N

FOXO1 (254-258) rabbit polyclonal antibody, Aff - Purified

Size: 50 ul 100 ul



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CNY 2,250.00


货期*
2周

规格
    • 100 ul

Product images

Specifications

Product Data
Applications IF, IHC, WB
Recommend Dilution Western blot: 1/500-1/1000.
Incubate membrane with diluted antibody in 5% nonfat milk, 1x TBS, 0.1%Tween-20 at 4°C with gentle shaking, obernight.
Immunofluorescence: 1/100-1/200.
Immunohistochemistry on Paraffin sections: 1/50-1/100.
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Peptide Sequence around amino acids 254~258 (A-A-S-M-D) derived from Human FKHR/FOXO1A
Specificity This antibody detects endogenous levels of total FKHR protein.
Formulation PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide and 50% Glycerol.
State: Aff - Purified
State: Liquid purified Ig fraction.
Concentration lot specific
Purification Immunoaffinity Chromatography using epitope-specific immunogen.
Conjugation Unconjugated
Storage Condition Store the antibody (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Predicted Protein Size 78-82 KDa
Gene Name forkhead box O1
Background FOXO1A (FKHR or ForkHead in Rhabdomyosarcoma) is a 70 kDa protein which is a member of a subfamily of the forkhead homeotic gene family of transcription factors. Recent studies have shown that this protein can act as either a coactivator or a corepressor of nuclear receptor activity. This action is mediated through the LXXLL motif found in the C terminus of the FOXO1A protein. The specific function of the gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Chromosomal aberrations involving FOXO1A are a cause of rhabdomyosarcoma 2 (RMS2); also known as alveolar rhabdomyosarcoma.
Synonyms Forkhead Box Protein O1, FOXO1, FKHR
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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