Histone H2A.X (H2AFX) pSer139 Rabbit Polyclonal Antibody

CAT#: AP02515PU-S

Histone H2A.X (H2AFX) pSer139 rabbit polyclonal antibody, Aff - Purified

Size: 50 ul 100 ul



Need it in bulk or conjugated?
Get a free quote

CNY 1,400.00


货期*
2周

规格
    • 50 ul

Product images

Specifications

Product Data
Applications IF, WB
Recommend Dilution Western Blot: 1/500-1/1000.
Immunofluorescence: 1/100-1/200.
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Histone H2A.X around the phosphorylation site of serine 139 (Q-A-SP-Q-E).
Specificity This antibody detects endogenous levels of Histone H2A.X only when
phosphorylated at Serine 139.
Formulation PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide and 50% Glycerol.
State: Aff - Purified
State: Liquid purified Ig fraction.
Concentration lot specific
Purification Affinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
Conjugation Unconjugated
Storage Condition Store the antibody (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Gene Name H2A histone family member X
Background Histone H2A.X is a member of the histone H2A family, 1 of 5 families of histone proteins involved in nucleosomal organization of chromatin. Histone H2A.X is synthesised in G1 as well as S phase and is known to be important for recombination between immunoglobulin switch regions. A very early step in the response of mammalian cells to DNA double strand breaks is the phosphorylation of Histone H2A.X at serine 139 at the sites of DNA damage. There is a predicted acetylation at residue 1 and ubiquitination at reside 119. Phosphorylated Histone H2A.X promotes DNA repair and maintains genomic stability.
Synonyms H2a/x, H2AFX, H2AX
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Customer Reviews 
Loading...