Low Density Lipoprotein / LDL Cu2+ oxidized Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC
Recommend Dilution	ELISA and related methods: 1/500-1/5,000 (Ref.1). Immunohistochemistry on Cryosections: 1/400 (Ref.1-4, 6). Immunohistochemistry on Paraffin Sections: < 1/500. See References for more details.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Human Cu2+-oxidized LDL
Specificity	Detects Human and Murine Cu2+-oxidized LDL. The antiserum shows strong reactivity to fully oxidized modifications of LDL including Cu2+-oxidized LDL, MDA-LDL, HOCL-LDL, but not to other oxidized proteins like MDA-HSA, MDA-HDL, HOCL-HSA, HOCL-HDL (below detection limit). The reaction to native LDL was weak, but clearly detectable (approx. 20%). Minimally oxidized LDL gave a strong binding signal (> 80%).
Formulation	State: Serum State: Lyophilized Serum
Reconstitution Method	Restore in aqua bidest to initial volume.
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Background	LDL (low-density lipoprotein) is a type of lipoprotein that transports cholesterol and triglycerides from the liver to peripheral tissues. LDL enables fats and cholesterol to move within the water based solution of the blood stream. LDL also regulates cholesterol synthesis at these sites.
Synonyms	Low-density lipoprotein
Reference Data

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