APRIL (TNFSF13) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	ELISA (1:50,000). Western blot (1:5,000).
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic APRIL (Tumor necrosis factor ligant superfamily member 13)
Specificity	This antibody detects APRIL.
Formulation	State: Serum State: Lyophilized serum
Reconstitution Method	Restore in aqua bidest to initial volume.
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2 - 8 °C and reconstituted at -20 °C. Avoid repeated freezing and thawing.
Gene Name	tumor necrosis factor superfamily member 13
Database Link	Entrez Gene 8741 Human UniProt ID O75888
Background	APRIL (A PRoliferation Inducing Ligand) a member of the TNF superfamily, is expressed in monocytes, macrophages, certain transformed cell lines, certain cancers of colon, and lymphoid tissues. Members of the TNF superfamily regulate immune responses and induce apoptosis. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.
Synonyms	TNFSF13, TALL2, TALL-2, ZTNF2, TRDL-1
Reference Data

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