Artemin (ARTN) Rabbit Polyclonal Antibody

CAT#: AP01145PU-N

Artemin (ARTN) rabbit polyclonal antibody, Aff - Purified

Size: 50 ug 100 ug

Conjugation: Unconjugated Biotin



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CNY 4,790.00


货期*
5周

规格
    • 100 ug

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Specifications

Product Data
Applications ELISA, WB
Recommend Dilution Indirect ELISA: To detect Human Artemin (using 100 μl/well antibody solution) a concentration of 0.5-2.0 μg/ml of this antibody is required. In conjunction with compatible secondary reagents, it allows the detection of at least 0.2-0.4 ng/well of recombinant Human Artemin.
Sandwich ELISA: To detect Human Artemin (using 100 μl/well antibody solution) a concentration of 0.5-2.0 μg/ml of this antibody is required. In conjunction with Biotinylated Anti-Human Artemin (Cat.Nr AP01145BT) as a Detection antibody, it allows the detection of at least 0.2-0.4 ng/well of recombinant Human Artemin.
Western blot: To detect Human Artemin this antibody can be used at a concentration of 0.1-0.2 µg/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant Human Artemin is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Highly pure (> 98%) derived recombinant Human Artemin
Specificity This antibody detects Artemin.
Formulation PBS, pH 7.2
State: Aff - Purified
State: Sterile filtered lyophilized Ig fraction
Reconstitution Method Centrifuge vial prior to opening.
Restore in sterile water to a concentration of 0.1-1.0 mg/ml.
Purification Immunoaffinity Chromatography
Conjugation Unconjugated
Storage Condition Store the lyophilized antibody at -20°C.
Following reconstitution it is stable for two weeks at 2-8°C.
Frozen aliquots are stable for 6 months when stored at -20°C.
Avoid repeated freezing and thawing.
Gene Name artemin
Background Artemin is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands, a group of ligands within the TGF-beta superfamily of signalling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenrative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Four alternatively spliced transcripts have been described, two of which encode the same protein.
Synonyms Enovin, Neublastin, ARTN, EVN
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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