Cardiac Troponin I (TNNI3) (69-86) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	Immunoassay: Use AP00830PU-N as a Detection Antibody in combination with AM05137PU-N as a Capture antibody in a Sandwich Immunoassay. Immunohistochemistry.
Reactivity	Human
Host	Goat
Clonality	Polyclonal
Immunogen	Highly purified Human Cardiac Troponin I
Specificity	This antibody is specific for Human Cardiac Troponin I. Recognizes epitopes located in the 69-86 region of Troponin I. Cross reactivity with Human skeletal Troponin I is < 1% by ELISA.
Formulation	10mM Sodium Phosphate, 0.85% (w/v) Sodium Chloride, pH 7.2 State: Aff - Purified State: Liquid purified Ig fraction (>95% pure) Preservative: 0.05% Sodium Azide
Concentration	lot specific
Purification	Affinity purified with Solid Phase Human Cardiac Troponin I peptide 4
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	troponin I3, cardiac type
Database Link	Entrez Gene 7137 Human UniProt ID P19429
Background	Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium.
Synonyms	TNNI3, TNNC1
Reference Data

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