PDE11A Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, IP, WB
Recommend Dilution	Immunohistochemistry. Immunoprecipitation. Western blot (1:5000).
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Designed from the C-terminal region common to all known 11A isoforms.
Specificity	The antibody selectively detects proteins corresponding to members of the PDE11A sub-family (Figure 1).
Formulation	State: Serum State: Liquid diluted serum
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	phosphodiesterase 11A
Database Link	Entrez Gene 50940 Human UniProt ID Q9HCR9
Background	Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3’, 5’-monophosphate (cAMP and cGMP). Thus, these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling. The PDE11 enzyme belongs to a family of PDEs able to hydrolyse both intracellular second messengers, cAMP and cGMP.
Synonyms	Phosphodiesterase 11A, PDE11A1, PDE11A2, PDE11A3, PDE11A4
Reference Data

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