PDE7A Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, IP, WB
Recommend Dilution	Western blot. Immunohistochemistry. Immunoprecipitation.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Designed from the C-terminal region common to the 7A isoform.
Specificity	The antibody selectively detects proteins corresponding to the PDE7A1 isoform.
Formulation	State: Serum State: Liquid diluted serum
Conjugation	Unconjugated
Storage Condition	Store at 4 °C. For long term storage, aliquot and store at -80 °C.
Gene Name	phosphodiesterase 7A
Database Link	Entrez Gene 5150 Human UniProt ID Q13946
Background	Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3', 5'- monophosphate (cAMP and cGMP). Thus, these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling. The PDE7 enzyme belongs to a family of cAMP-dependent PDEs that provide the major means of inactivating the key intracellular second messenger, cAMP. Two genes (PDE7A and PDE7B) encode the PDE7 family, each with multiple splice variants.
Synonyms	Phosphodiesterase 7A, PDE7, HCP1, TM22
Reference Data

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