CD1 (CD1A) Mouse Monoclonal Antibody [Clone ID: O10+C1A/711]

CAT#: AM50211PU-S

CD1 (CD1A) mouse monoclonal antibody, clone O10+C1A/711, Purified

Size: 20 ug 100 ug



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CNY 5,830.00


货期*
5周

规格
    • 100 ug

Product images

Specifications

Product Data
Clone Name O10+C1A/711
Applications FC, IF, IHC, IP, WB
Recommend Dilution Flow Cytometry: 0.5-1 μg/million cells.
Immunofluorescence: 1-2 μg/ml.
Immunoprecipitation: 1-2 μg/500 μg protein.
Western Blotting: 0.5-1 μg/ml.
Immunohistochemistry on Frozen and Formalin-Fixed Paraffin Sections: 0.5-1 μg/ml for 30 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM
Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
Positive Control: MOLT-4 cells. Paracortex in a tonsil or a reactive lymph node.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Human thymus cells (O10); Recombinant Human CD1a protein (C1A/711).
Specificity Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa).
Cellular Localization: Cell surface.
Formulation 10mM PBS
State: Purified
State: Liquid purified IgG fraction from Bioreactor Concentrate
Stabilizer: 0.05% BSA
Preservative: 0.05% Sodium Azide
Concentration lot specific
Purification Protein A/G Chromatography
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C.
Predicted Protein Size 49 kDa
Gene Name CD1a molecule
Background At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin.
Synonyms T6/Leu-6, hTa1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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