Cytokeratin 19 (KRT19) (1-400) Mouse Monoclonal Antibody [Clone ID: AT13D10]

Specifications

Product Data
Clone Name	AT13D10
Applications	ELISA, FC, IF, WB
Recommend Dilution	ELISA. Western blot: starting dilution is 1:1000. Immunocytochemstry / Immunoflourescence. Flow cytometry.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human KRT19 (1-400aa) purified from E. coli
Specificity	This antibody detects Human KRT19 (1-400aa). Other species not tested.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified IgG fraction
Concentration	lot specific
Purification	Protein-A affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	keratin 19
Database Link	Entrez Gene 3880 Human UniProt ID P08727
Background	KRT19 (type 1 cytokeratin 19) is 44kDa intermediate filament (IF) protein that is part of the Keratin family of proteins. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells and have been found to be useful markers of tissue differentiation. KRT19 is an important biomarker for breast cancer cells, tumor cells of the lymph nodes, peripheral blood, and bone marrow. Cytokeratin 19 can be expressed with KRT8 and KRT18 to differentiate cells of epithelial lines from hematopoietic tumor cells in the peripheral blood.
Synonyms	Cytokeratin-19, Keratin-19, KRT19, CK19, K19
Reference Data

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