IL12A Mouse Monoclonal Antibody [Clone ID: B-S35]

CAT#: AM32424AF-N

IL12A mouse monoclonal antibody, clone B-S35, Azide Free



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CNY 7,183.00


货期*
5周

规格
    • 500 ug

Product images

Specifications

Product Data
Clone Name B-S35
Applications ELISA
Recommend Dilution ELISA.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen EBI3 recombinant protein and IL-35/Fc recombinant protein.
Myeloma X63/AG.8653 x Balb/c node cells.
Specificity Recognises both natural and recombinant protein (no cross reaction with IL-12 and IL-27).
Formulation PBS without carriers and preservatives
State: Azide Free
State: Liquid purified (0.2 μm sterile filtered) IgG fraction
Concentration lot specific
Purification Ion Exchange Chromatography
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C.
Gene Name interleukin 12A
Background IL-35 or Interleukin 35 is a cytokine belonging to the IL12 family, that is produced by regulatory T cells. It is a dimeric protein composed of IL-12-alpha and IL-27-beta chains. Members of this class of cytokines are important in influencing T helper cell differentiation and supressing inflammatory response. IL-35 is known to play an essential role in immune regulation of the CD4+CD25+ regulatory T (Treg) cells, from which IL-35 is also specifically produced. IL-35 is able to expand CD4+CD25+ Treg cells whereas it can inhibit proliferation of CD4+CD25- effector T (Teff) cells and development of proinflammatory Th17 cells, suppressing inflammatory responses.
Synonyms IL-12A, IL-12 subunit p35, NKSF1, CLMF p35
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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