CD90 (THY1) Mouse Monoclonal Antibody [Clone ID: AF-9]

Specifications

Product Data
Clone Name	AF-9
Applications	ELISA, IHC
Recommend Dilution	ELISA. Flow Cytometry. Immunohistochemistry on frozen sections.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	T cell lymphoma cells.
Specificity	This antibody reacts to CD90.
Formulation	PBS State: Purified State: Liquid purified Ig fraction Preservative: 0.05% sodium azide
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Gene Name	Thy-1 cell surface antigen
Database Link	Entrez Gene 7070 Human UniProt ID P04216
Background	CD90 is also known as Thy-1 antigen and a member of the immunoglobulin superfamily. It may contribute to inhibition of proliferation/differentiation of hematopoietic stem cells and neuron memory formation in the CNS. It consists of a single Ig domain (112 amino acids; 25-35 kD) inserted into the cell membrane via a GPI anchor. Expressed by hematopoietic stem cells and neurons in all species studied. Its highly expressed in connective tissue and various fibroblast and stromal cell lines, expressed on all thymocytes and peripheral T cells in mice, but in humans expressed only on small % fetal thymocytes, 10-40% of CD34+ cells in bone marrow, and <1% of CD3+CD4+ lymphocytes in peripheral circulation. It is also expressed by human lymph node HEV endothelium but not other endothelia. Lastly, it is expressed by a limited number of lymphoblastoid and leukemic cell lines.
Synonyms	Thy-1, THY1, CDw90
Reference Data

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