Mucin-16 / CA125 Mouse Monoclonal Antibody [Clone ID: OC125]
CAT#: AM32272SU-N
Mucin-16 / CA125 mouse monoclonal antibody, clone OC125, Supernatant
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CNY 22,838.00
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Specifications
Product Data | |
Clone Name | OC125 |
Applications | IHC |
Recommend Dilution | Immunohistochemistry on Frozen Sections. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Specificity | This CA125 antibody clone OC125 reacts with epithelioid malignancies of the ovary, papillary serous carcinoma of the cervix, adenocarcinoma of the endometrium, clear cell adenocarcinoma of the bladder, and epithelioid mesothelioma. The antigen is formalin resistant, permitting the detection of ovarian cancer by immunohistochemistry, although serum assays for this protein are widely used to monitor ovarian cancer. This antibody also reacts with antigens in seminal vesicle carcinoma. |
Formulation | PBS, pH 7.4 State: Supernatant State: Liquid Tissue Culture Supernatant Stabilizer: 0.9% BSA Preservative: 0.09% Sodium Azide |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | mucin 16, cell surface associated |
Database Link | |
Background | CA125/MUC16 antigen is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. It is a mullerian duct differentiation antigen that is overexpressed in epithelial ovarian cancer cells and secreted into the blood, although its expression is not entirely confined to ovarian cancer. Most biochemical studies have concluded that CA125/MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa. |
Synonyms | MUC16, MUC-16, CA-125, CA 125 |
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