EMA (MUC1) Mouse Monoclonal Antibody [Clone ID: 139H2]

Specifications

Product Data
Clone Name	139H2
Applications	ELISA, EM, FC, IF, IHC, IP, WB
Recommend Dilution	ELISA. Western blot. Electron Microscopy. Flow Cytometry. Immunofluorescence. Immunoprecipitation. Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections: 10 µg/ml.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human milk-fat globule membranes (HMFGM).
Specificity	This Mouse monoclonal antibody has been raised against Human milk-fat globule membranes (HMFGM) to obtain reagents for mammary tumor diagnosis. This monoclonal reacts towards an peptide epitope in the repeat region of MUC-1.
Formulation	PBS State: Purified State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	mucin 1, cell surface associated
Database Link	Entrez Gene 4582 Human UniProt ID P15941
Background	Mucin 1, cell surface associated (MUC-1) or polymorphic epithelial mucin (PEM) is a mucin encoded by the MUC1 gene in humans. MUC-1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with colon, breast, ovarian, lung and pancreatic cancers.
Synonyms	MUC-1, PEMT, Episialin, EMA, H23AG, PUM, DF3, CA 15-3
Reference Data

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