Thrombomodulin (THBD) Mouse Monoclonal Antibody [Clone ID: B-S24]
CAT#: AM31361AF-N
Thrombomodulin (THBD) mouse monoclonal antibody, clone B-S24, Azide Free
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CNY 3,806.00
货期*
5周
规格
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Specifications
Product Data | |
Clone Name | B-S24 |
Applications | ELISA |
Recommend Dilution | ELISA. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Eahy 926 cell lines. |
Specificity | Recognises Thrombomodulin (TM), a 105 kDa protein. |
Formulation | 0.22 µm Sterile-filtered PBS. Carrier and preservative free. State: Azide Free State: Liquid purified IgG fraction |
Concentration | lot specific |
Purification | Ion Exchange Chromatography |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for up to 12 months. For longer storage freeze aliquots. |
Gene Name | thrombomodulin |
Database Link | |
Background | CD141/Thrombomodulin is an exclusively endothelial cell surface glycoprotein that forms a 1:1 complex with thrombin. Binding of thrombin to this high-affinity receptor alters its specificity toward several substrates. The complex activates protein C approximately 1000 times faster than thrombin alone. Activated protein C degrades clotting factors V and VIII; thus, thrombomodulin converts thrombin into a physiologic anticoagulant. Thrombomodulin is also found in the circulatory and urinary systems, the physiologic significance of this is obscure. |
Synonyms | Thrombomodulin, THRM, Fetomodulin |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Complement and coagulation cascades |
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