ICAM2 Mouse Monoclonal Antibody [Clone ID: B-T1]

Specifications

Product Data
Clone Name	B-T1
Applications	FC, IP
Recommend Dilution	Flow Cytometry: Use 10 µl to label 10e6 cells or 100 µl of whole blood. Immunoprecipitation. This Clone has been described to work in Western Blot and Immunofluorescence.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	ICAM-2 transfected CHO cells.
Specificity	Recognises the Intercellular Adhesion Molecule-2 (ICAM-2), a 55-65 kDa protein.
Formulation	PBS containing 1 % BSA as stabilizer and 0.09% Sodium Azide as preservative State: Purified State: Liquid purified IgG fraction
Purification	Ion Exchange Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	intercellular adhesion molecule 2
Database Link	Entrez Gene 3384 Human UniProt ID P13598
Background	ICAM2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin like C2 type domains, and bind to the leukocyte adhesion LFA1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA1 dependent cell adhesion. It mediates adhesive interactions important for antigen specific immune response, NK cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
Synonyms	ICAM-2
Reference Data
Protein Families	ES Cell Differentiation/IPS, Transmembrane
Protein Pathways	Cell adhesion molecules (CAMs), Natural killer cell mediated cytotoxicity

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